Seth Bordenstein
- Dorothy Foehr Huck and J. Lloyd Huck Endowed Chair in Microbiome Sciences
- Director of the Microbiome Center
- Professor of Biology and Entomology
Pennsylvania State University
W-251 Millennium Science Complex
Pollock Road
University Park, PA 16802
- Email s.bordenstein@psu.edu
- Office 1.814.865.1100
Areas of Expertise
- Endosymbiosis, Microbiome, Evolution, Phage Biology
Education
- Postdoc, Bay Paul Center for Comparative Molecular Biology and Evolution, Marine Biological Lab, Woods Hole MA
- Ph.D., Evolutionary Symbiosis, University of Rochester, Rochester NY
- M.S., Evolutionary Genetics, University of Rochester, Rochester NY
- B.S., Ecology and Evolutionary Biology, Biological Sciences | University of Rochester, Rochester NY
*We are recruiting at all levels spanning lab manager, postdocs, and research professors; Please contact Dr. Bordenstein at s.bordenstein@psu.edu with a single pdf including cover letter, CV, and 1st authored papers, reports, and presentations. For more information on these projects and the lab, please visit https://bordensteinlab.com | See the jobXriv ad for more info*
Dr. Bordenstein has studied animal-microbe symbioses and microbiomes for 25 years. He is an evolutionary geneticist and microbiologist in the Departments of Entomology and Biology at Pennsylvania State University (PSU), University Park, PA. He is the the director of the PSU Microbiome Center and formerly the founding director of the Vanderbilt Microbiome Innovation Center and the worldwide HHMI-initiated science education program Discover the Microbes Within! The Wolbachia Project. He is also the Dorothy Foehr Huck and J. Lloyd Huck Endowed Chair in Microbiome Sciences.
The Bordenstein laboratory endeavors to understand the evolutionary and genetic principles that shape symbiotic interactions between animals, microbes, and viruses and the major applications of these interactions to human health. Towards these goals, the lab employs hypothesis-driven approaches to molecularly unravel intimate symbioses between arthropods and obligate intracellular bacteria that modify sexual reproduction and facultative symbioses between animals and gut microbes that impact animal health, fitness, and evolution. The lab is helping to solve the next generation of endosymbiosis and microbiome challenges by (i) discovering the selfish bacteriophage WO genes, cytoplasmic incompatibility factor (cifA and cifB) and WO mediated killing (wmk), that alter arthropod sexual reproduction, (ii) establishing and coining the framework for phylosymbiosis, which is a cross-system host-microbiome pattern, (iii) revealing the first antibacterial gene from Archaea, and (iv) studying the persistent association of self-identified ethnicity and race with human microbiome variation in the United States.
Dr. Bordenstein is the recipient of the 2014 Jeffrey Nordhaus Award for Excellence in Undergraduate Teaching, 2014 Chancellor’s Award for Research, 2018 Chancellor Faculty Fellow Award from Vanderbilt University, and 2020 Genetics Society of America Award for Excellence in Education.
Publications
Prophage proteins alter long noncoding RNA and DNA of developing sperm to induce a paternal-effect lethality
Science, Kaur, Rupinder, McGarry, Angelina, Dylan Shropshire, J., Leigh, Brittany A., Bordenstein, Seth R., 2024
The mechanism of cytoplasmic incompatibility is conserved in Wolbachia-bearing Aedes aegypti mosquitoes deployed for arbovirus control
PLoS Biology, Kaur, Rupinder, Meier, Cole J., McGraw, Elizabeth A., Hillyer, Julian F., Bordenstein, Seth R., 2024
It is time to authenticate the Microbiome Sciences with accredited educational programs and departments
PLoS Biology, Ginnan, Nichole, Bordenstein, Seth R., 2023
Human microbiome variation associated with race and ethnicity emerges as early as 3 months of age
PLoS Biology, Mallott, Elizabeth K., Sitarik, Alexandra R., Leve, Leslie D., Cioffi, Camille, Camargo, Carlos A., Hasegawa, Kohei, Bordenstein, Seth R., 2023
Low Gut Microbial Diversity Augments Estrogen-Driven Pulmonary Fibrosis in Female-Predominant Interstitial Lung Disease
Cells, Chioma, Ozioma S., Mallott, Elizabeth, Shah-Gandhi, Binal, Wiggins, Za Darreyal, Langford, Madison, Lancaster, Andrew William, Gelbard, Alexander, Wu, Hongmei, Johnson, Joyce E., Lancaster, Lisa, Wilfong, Erin M., Crofford, Leslie J., Montgomery, Courtney G., Van Kaer, Luc, Bordenstein, Seth, Newcomb, Dawn C., Drake, Wonder Puryear, 2023
Gut microbiota modulates lung fibrosis severity following acute lung injury in mice
Communications Biology, Chioma, Ozioma S., Mallott, Elizabeth K., Chapman, Austin, Van Amburg, Joseph C., Wu, Hongmei, Shah-Gandhi, Binal, Dey, Nandita, Kirkland, Marina E., Blanca Piazuelo, M., Johnson, Joyce, Bernard, Gordon R., Bodduluri, Sobha R., Davison, Steven, Haribabu, Bodduluri, Bordenstein, Seth R., Drake, Wonder P., 2022
Transgenic cytoplasmic incompatibility persists across age and temperature variation in Drosophila melanogaster
iScience, Ritchie, Isabella T., Needles, Kelly T., Leigh, Brittany A., Kaur, Rupinder, Bordenstein, Seth R., 2022
Individuality and ethnicity eclipse a short-term dietary intervention in shaping microbiomes and viromes
PLoS Biology, Li, Junhui, Markowitz, Robert H.George, Brooks, Andrew W., Mallott, Elizabeth K., Leigh, Brittany A., Olszewski, Timothy, Zare, Hamid, Bagheri, Minoo, Smith, Holly M., Friese, Katie A., Habibi, Ismail, Lawrence, William M., Rost, Charlie L., Lédeczi, Ákos, Eeds, Angela M., Ferguson, Jane F., Silver, Heidi J., Bordenstein, Seth R., 2022
Microbiome-associated human genetic variants impact phenome-wide disease risk
Proceedings of the National Academy of Sciences of the United States of America, Markowitz, Robert H.George, LaBella, Abigail Leavitt, Shi, Mingjian, Rokas, Antonis, Capra, John A., Ferguson, Jane F., Mosley, Jonathan D., Bordenstein, Seth R., 2022
A Margulian View of Symbiosis and Speciation: the Nasonia Wasp System
Symbiosis, Bell, Kara, Bordenstein, Seth R., 2022
The Cif proteins from Wolbachia prophage WO modify sperm genome integrity to establish cytoplasmic incompatibility
PLoS Biology, Kaur, Rupinder, Leigh, Brittany A., Ritchie, Isabella T., Bordenstein, Seth R., 2022
Comparison of qPCR and dPCR methods for the quantification of Wolbachia densities and arthropod gene expression.
Qiagen Application Note, Cross, K.L., Bordenstein, Seth, 2022
Widespread phages of endosymbionts: Phage WO genomics and the proposed taxonomic classification of Symbioviridae
PLoS Genetics, Bordenstein, Sarah, Bordenstein, Seth R., 2022
A single synonymous nucleotide change impacts the male-killing phenotype of prophage wo gene wmk
eLife, Perlmutter, Jessamyn I., Meyers, Jane E., Bordenstein, Seth R., 2021
The microbiome impacts host hybridization and speciation
PLoS Biology, Miller, Asia K., Westlake, Camille S., Cross, Karissa L., Leigh, Brittany A., Bordenstein, Seth R., 2021
New-onset vegetarian diet shows differences in fatty acid metabolites in European American and African American women
Nutrition, Metabolism and Cardiovascular Diseases, Wang, Naomi C., Bagheri, Minoo, Olszewski, Timothy, Friese, Katie A., Smith, Holly M., Robles, Michelle E., Wang, Chuan, Brooks, Andrew, Bordenstein, Seth R., Ferguson, Jane F., Silver, Heidi J., 2021
Microbiome reduction and endosymbiont gain from a switch in sea urchin life history
Proceedings of the National Academy of Sciences of the United States of America, Carrier, Tyler J., Leigh, Brittany A., Deaker, Dione J., Devens, Hannah R., Wray, Gregory A., Bordenstein, Seth R., Byrne, Maria, Reitzel, Adam M., 2021
Genomes of gut bacteria from nasonia wasps shed light on phylosymbiosis and microbe-assisted hybrid breakdown
mSystems, Cross, Karissa L., Leigh, Brittany A., Hatmaker, E. Anne, Mikaelyan, Aram, Miller, Asia K., Bordenstein, Seth R., 2021
Living in the endosymbiotic world of Wolbachia: A centennial review
Cell Host and Microbe, Kaur, R, Shropshire, J, Cross, Karissa, Leigh, Brittany, Mansueto, Alexander, Stewart, Victoria, Bordenstein, Sarah, Bordenstein, Seth R., 2021
The impacts of cytoplasmic incompatibility factor (cifA and cifB) genetic variation on phenotypes
Genetics, Shropshire, J. Dylan, Rosenberg, Rachel, Bordenstein, Seth R., 2021
The impact of artificial selection for wolbachia-mediated dengue virus blocking on phage wo
PLoS Neglected Tropical Diseases, Dutra, Heverton, Ford, Suzanne, Allen, Scott, Bordenstein, Sarah, Chenoweth, Stephen, Bordenstein, Seth, McGraw, Elizabeth A., 2021
Symbiont-mediated cytoplasmic incompatibility: What have we learned in 50 years?
eLife, Shropshire, J. Dylan, Leigh, Brittany, Bordenstein, Seth R., 2020
Evolution-guided mutagenesis of the cytoplasmic incompatibility proteins: Identifying CifA’s complex functional repertoire and new essential regions in CifB
PLoS Pathogens, Shropshire, J. Dylan, Kalra, Mahip, Bordenstein, Seth R., 2020
Visualizing the invisible: class excursions to ignite children’s enthusiasm for microbes
Microbial Biotechnology, McGenity, Terry J., Gessesse, Amare, Hallsworth, John E., Garcia Cela, Esther, Verheecke-Vaessen, Carol, Wang, Fengping, Chavarría, Max, Haggblom, Max M., Molin, Søren, Danchin, Antoine, Smid, Eddy J., Lood, Cédric, Cockell, Charles S., Whitby, Corinne, Liu, Shuang Jiang, Keller, Nancy P., Stein, Lisa Y., Bordenstein, Seth R., Lal, Rup, Nunes, Olga C., Gram, Lone, Singh, Brajesh K., Webster, Nicole S., Morris, Cindy, Sivinski, Sharon, Bindschedler, Saskia, Junier, Pilar, Antunes, André, Baxter, Bonnie K., Scavone, Paola, Timmis, Kenneth, 2020
An introduction to phylosymbiosis
Proceedings of the Royal Society B: Biological Sciences, Lim, Shen Jean, Bordenstein, Seth R., 2020
Microorganisms in the reproductive tissues of arthropods
Nature Reviews Microbiology, Perlmutter, Jessamyn I., Bordenstein, Seth R., 2020
Discover the microbes within! The wolbachia project: Citizen science and student-based discoveries for 15 years and counting
Genetics, Lemon, Athena, Bordenstein, Sarah, Bordenstein, Seth R., 2020
Reply to Kenyon, “Are differences in the oral microbiome due to ancestry or socioeconomics?”
mSystems, Yang, Yaohua, Zheng, Wei, Cai, Qiuyin, Shrubsole, Martha J., Pei, Zhiheng, Brucker, Robert, Steinwandel, Mark, Bordenstein, Seth R., Li, Zhigang, Blot, William J., Shu, Xiao Ou, Long, Jirong, 2020
Transgenic testing does not support a role for additional candidate genes in Wolbachia male killing or cytoplasmic incompatibility
mSystems, Perlmutter, Jessamyn I., Meyers, Jane E., Bordenstein, Seth R., 2020
The emergence of microbiome centres
Nature Microbiology, Martiny, Jennifer, Whiteson, Katrine, Bohannan, Brendan, David, Lawrence, Hynson, Nicole, McFall-Ngai, Margaret, Rawls, John, Schmidt, Thomas, Abdo, Zaid, Blaser, Martin, Bordenstein, Seth, Bréchot, Christian, Bull, Carolee T., Dorrestein, Pieter, Eisen, Jonathan, Garcia-Pichel, Ferran, Gilbert, Jack, Hofmockel, Kirsten, Holtz, Mary, Knight, Rob, Mark Welch, David, McDonald, Daniel, Methé, Barbara, Mouncey, Nigel, Mueller, Noel, Pfister, Catherine, Proctor, Lita, Sachs, Joel, 2020
Author Correction: The Wolbachia mobilome in Culex pipiens includes a putative plasmid (Nature Communications, (2019), 10, 1, (1051), 10.1038/s41467-019-08973-w)
Nature Communications, Reveillaud, Julie, Bordenstein, Sarah R., Cruaud, Corinne, Shaiber, Alon, Esen, Özcan C., Weill, Mylène, Makoundou, Patrick, Lolans, Karen, Watson, Andrea R., Rakotoarivony, Ignace, Bordenstein, Seth R., Eren, A. Murat, 2019
Cigarette smoking and oral microbiota in low-income and African-American populations
Journal of Epidemiology and Community Health, Yang, Yaohua, Zheng, Wei, Cai, Qiu Yin, Shrubsole, Martha J., Pei, Zhiheng, Brucker, Robert, Steinwandel, Mark D., Bordenstein, Seth R., Li, Zhigang, Blot, William J., Shu, Xiao Ou, Long, Jirong, 2019
Paternal grandmother age affects the strength of Wolbachia-induced cytoplasmic incompatibility in Drosophila melanogaster
mBio, Layton, Emily M., On, Jungmin, Perlmutter, Jessamyn I., Bordenstein, Seth R., Shropshire, J. Dylan, 2019
Microbiota and the social brain
Science, Sherwin, Eoin, Bordenstein, Seth R., Quinn, John L., Dinan, Timothy G., Cryan, John F., 2019
Phylosymbiosis impacts adaptive traits in nasonia wasps
mBio, van Opstal, Edward J., Bordenstein, Seth R., 2019
Two-by-one model of cytoplasmic incompatibility: Synthetic recapitulation by transgenic expression of cifa and cifb in drosophila
PLoS Genetics, Shropshire, J. Dylan, Bordenstein, Seth R., 2019
Corrigendum: Evolutionary genetics of cytoplasmic incompatibility genes cifA and cifB in prophage WO of Wolbachia (Genome Biology and Evolution (2018) 10 (434-451) DOI: 10.1093/gbe/evy012)
Genome Biology and Evolution, Lindsey, Amelia R.I., Rice, Danny W., Bordenstein, Sarah R., Brooks, Andrew W., Bordenstein, Seth R., Newton, Irene L.G., 2019
The phage gene wmk is a candidate for male killing by a bacterial endosymbiont
PLoS Pathogens, Perlmutter, Jessamyn, Bordenstein, Sarah, Unckless, Robert, LePage, Daniel, Metcalf, Jason, Hill, Tom, Martinez, Julien, Jiggins, Francis, Bordenstein, Seth R., 2019
Minimum information about an uncultivated virus genome (MIUVIG)
Nature Biotechnology, Roux, Simon, Adriaenssens, Evelien M., Dutilh, Bas E., Koonin, Eugene V., Kropinski, Andrew M., Krupovic, Mart, Kuhn, Jens H., Lavigne, Rob, Brister, J. Rodney, Varsani, Arvind, Amid, Clara, Aziz, Ramy K., Bordenstein, Seth R., Bork, Peer, Breitbart, Mya, Cochrane, Guy R., Daly, Rebecca A., Desnues, Christelle, Duhaime, Melissa B., Emerson, Joanne B., Enault, François, Fuhrman, Jed A., Hingamp, Pascal, Hugenholtz, Philip, Hurwitz, Bonnie L., Ivanova, Natalia N., Labonté, Jessica M., Lee, Kyung Bum, Malmstrom, Rex R., Martinez-Garcia, Manuel, Mizrachi, Ilene Karsch, Ogata, Hiroyuki, Páez-Espino, David, Petit, Marie Agnès, Putonti, Catherine, Rattei, Thomas, Reyes, Alejandro, Rodriguez-Valera, Francisco, Rosario, Karyna, Schriml, Lynn, Schulz, Frederik, Steward, Grieg F., Sullivan, Matthew B., Sunagawa, Shinichi, Suttle, Curtis A., Temperton, Ben, Tringe, Susannah G., Thurber, Rebecca Vega, Webster, Nicole S., Whiteson, Katrine L., Wilhelm, Steven W., Wommack, K. Eric, Woyke, Tanja, Wrighton, Kelly C., Yilmaz, Pelin, Yoshida, Takashi, Young, Mark J., Yutin, Natalya, Allen, Lisa Zeigler, Kyrpides, Nikos C., Eloe-Fadrosh, Emiley A., 2019
Racial differences in the oral microbiome: Data from low-income populations of African ancestry and European ancestry
mSystems, Yang, Yaohua, Zheng, Wei, Cai, Qiuyin, Shrubsole, Martha J., Pei, Zhiheng, Brucker, Robert, Steinwandel, Mark, Bordenstein, Seth R., Li, Zhigang, Blot, William J., Shu, Xiao Ou, Long, Jirong, 2019
Models and Nomenclature for Cytoplasmic Incompatibility: Caution over Premature Conclusions – A Response to Beckmann et al.
Trends in Genetics, Shropshire, J, Leigh, Brittany, Bordenstein, Sarah, Duplouy, Anne, Riegler, Markus, Brownlie, Jeremy, Bordenstein, Seth R., 2019
The Wolbachia mobilome in Culex pipiens includes a putative plasmid
Nature Communications, Reveillaud, Julie, Bordenstein, Sarah, Cruaud, Corinne, Shaiber, Alon, Esen, Özcan C., Esen, \"Ozcan C, None, Weill, Mylène, Weill, Myl\`ene, None, Makoundou, Patrick, Lolans, Karen, Watson, Andrea, Rakotoarivony, Ignace, Bordenstein, Seth R., others, None, Eren, A. Murat, 2019
Gut microbiota diversity across ethnicities in the United States
PLoS Biology, Brooks, Andrew W., Priya, Sambhawa, Blekhman, Ran, Bordenstein, Seth R., 2018
Microbe profile: Wolbachia: A sex selector, a viral protector and a target to treat filarial nematodes
Journal of General Microbiology, Taylor, Mark J., Bordenstein, Seth R., Slatko, Barton, 2018
Distinct mucosal microbial communities in infants with surgical necrotizing enterocolitis correlate with age and antibiotic exposure
PLoS One, Romano-Keeler, Joann, Shilts, Meghan H., Tovchigrechko, Andrey, Wang, Chunlin, Brucker, Robert M., Moore, Daniel J., Fonnesbeck, Christopher, Meng, Shufang, Correa, Hernan, Lovvorn, Harold N., Tang, Yi Wei, Hooper, Lora, Bordenstein, Seth R., Das, Suman R., Weitkamp, Jorn Hendrik, 2018
Microbial Misandry: Discovery of a Spiroplasma Male-Killing Toxin
Cell Host and Microbe, Perlmutter, Jessamyn I., Bordenstein, Seth R., 2018
The Maternal Effect Gene Wds Controls Wolbachia Titer in Nasonia
Current Biology, Funkhouser-Jones, Lisa J., van Opstal, Edward J., Sharma, Ananya, Bordenstein, Seth R., 2018
One prophage WO gene rescues cytoplasmic incompatibility in Drosophila melanogaster
Proceedings of the National Academy of Sciences of the United States of America, Dylan Shropshire, J., On, Jungmin, Layton, Emily M., Zhou, Helen, Bordenstein, Seth R., 2018
Microbial communities exhibit host species distinguishability and phylosymbiosis along the length of the gastrointestinal tract
Molecular Ecology, Kohl, Kevin D., Dearing, M. Denise, Bordenstein, Seth R., 2018
Gut microbes limit growth in house sparrow nestlings (Passer domesticus) but not through limitations in digestive capacity
Integrative Zoology, Kohl, Kevin D., Brun, Antonio, Bordenstein, Seth R., Caviedes-Vidal, Enrique, Karasov, William H., 2018
Finer-scale phylosymbiosis: Insights from insect viromes
mSystems, Leigh, Brittany, Bordenstein, Sarah, Brooks, Andrew, Mikaelyan, Aram, Bordenstein, Seth R., 2018
Evolutionary Genetics of Cytoplasmic Incompatibility Genes cifA and cifB in Prophage WO of Wolbachia
Genome Biology and Evolution, Lindsey, Amelia, Rice, Danny, Bordenstein, Sarah, Brooks, Andrew, Bordenstein, Seth, Newton, Irene, 2018
Chromosomal localization of Wolbachia inserts in the genomes of two subspecies of Chorthippus parallelus forming a Pyrenean hybrid zone
Chromosome Research, Toribio-Fernández, Raquel, Bella, José L., Martínez-Rodríguez, Paloma, Funkhouser-Jones, Lisa J., Bordenstein, Seth R., Pita, Miguel, 2017
Parasite microbiome project: Systematic investigation of microbiome dynamics within and across parasite-host interactions
mSystems, Dheilly, Nolwenn M., Bolnick, Daniel, Bordenstein, Seth, Brindley, Paul J., Figuères, Cédric, Holmes, Edward C., Martínez, Joaquín Martínez, Phillips, Anna J., Poulin, Robert, Rosario, Karyna, 2017
Association of oral microbiome with type 2 diabetes risk
Journal of Periodontal Research, Long, J., Cai, Q., Steinwandel, M., Hargreaves, M. K., Bordenstein, S. R., Blot, W. J., Zheng, W., Shu, X. O., 2017
Gut microbial ecology of lizards: insights into diversity in the wild, effects of captivity, variation across gut regions and transmission
Molecular Ecology, Kohl, Kevin D., Brun, Antonio, Magallanes, Melisa, Brinkerhoff, Joshua, Laspiur, Alejandro, Acosta, Juan Carlos, Caviedes-Vidal, Enrique, Bordenstein, Seth R., 2017
Establishment of F1 hybrid mortality in real time
BMC Evolutionary Biology, Saulsberry, Ashley, Pinchas, Marisa, Noll, Aaron, Lynch, Jeremy A., Bordenstein, Seth R., Brucker, Robert M., 2017
Correction to: Phylosymbiosis: Relationships and Functional Effects of Microbial Communities across Host Evolutionary History (PLOS Biology, (2016), 14, 11, (e2000225), 10.1371/journal.pbio.2000225)
PLoS Biology, Brooks, Andrew W., Kohl, Kevin D., Brucker, Robert M., van Opstal, Edward J., Bordenstein, Seth R., 2017
Prophage WO genes recapitulate and enhance Wolbachia-induced cytoplasmic incompatibility
Nature, LePage, Daniel, Le Page, Daniel P., Metcalf, Jason, Bordenstein, Sarah, On, Jungmin, Perlmutter, Jessamyn, Shropshire, J, Layton, Emily, Funkhouser-Jones, Lisa, Beckmann, John, Bordenstein, Seth R., 2017
Phylosymbiosis: Relationships and Functional Effects of Microbial Communities across Host Evolutionary History
PLoS Biology, Brooks, Andrew W., Kohl, Kevin D., Brucker, Robert M., van Opstal, Edward J., Bordenstein, Seth R., 2016
Disentangling a holobiont - recent advances and perspectives in Nasonia wasps
Frontiers in Microbiology, Dittmer, Jessica, van Opstal, Edward J., Shropshire, J. Dylan, Bordenstein, Seth R., Hurst, Gregory D.D., Brucker, Robert M., 2016
Fecal Transplants: What Is Being Transferred?
PLoS Biology, Bojanova, Diana P., Bordenstein, Seth R., 2016
Physiological and microbial adjustments to diet quality permit facultative herbivory in an omnivorous lizard
Journal of Experimental Biology, Kohl, Kevin D., Brun, Antonio, Magallanes, Melisa, Brinkerhoff, Joshua, Laspiur, Alejandro, Acosta, Juan Carlos, Bordenstein, Seth R., Caviedes-Vidal, Enrique, 2016
Wolbachia pipientis should not be split into multiple species: A response to Ramírez-Puebla et al.
Systematic and Applied Microbiology, Lindsey, Amelia R.I., Bordenstein, Seth R., Newton, Irene L.G., Rasgon, Jason L., 2016
Comparative genomics of two closely related wolbachia with different reproductive effects on hosts
Genome Biology and Evolution, Newton, Irene L.G., Clark, Michael E., Kent, Bethany N., Bordenstein, Seth R., Qu, Jiaxin, Richards, Stephen, Kelkar, Yogeshwar D., Werren, John H., 2016
Wolbachia mosquito control: Regulated
Science, Dobson, Stephen L., Bordenstein, Seth R., Rose, Robert I., 2016
Airway bacteria drive a progressive COPD-like phenotype in mice with polymeric immunoglobulin receptor deficiency
Nature Communications, Richmond, Bradley W., Brucker, Robert M., Han, Wei, Du, Rui Hong, Zhang, Yongqin, Cheng, Dong Sheng, Gleaves, Linda, Abdolrasulnia, Rasul, Polosukhina, Dina, Clark, Peter E., Bordenstein, Seth R., Blackwell, Timothy S., Polosukhin, Vasiliy V., 2016
Speciation by symbiosis: The microbiome and behavior
mBio, Shropshire, J. Dylan, Bordenstein, Seth R., 2016
Getting the hologenome concept right: An eco-evolutionary framework for hosts and their microbiomes
mSystems, Theis, Kevin R., Dheilly, Nolwenn M., Klassen, Jonathan L., Brucker, Robert M., Baines, John F., Bosch, Thomas C.G., Cryan, John F., Gilbert, Scott F., Goodnight, Charles J., Lloyd, Elisabeth A., Sapp, Jan, Vandenkoornhuyse, Philippe, Zilber-Rosenberg, Ilana, Rosenberg, Eugene, Bordenstein, Seth R., 2016
Eukaryotic association module in phage WO genomes from Wolbachia
Nature Communications, Bordenstein, Sarah, Bordenstein, Seth R., 2016
An optimized approach to germ-free rearing in the jewel wasp Nasonia
PeerJ, Shropshire, J. Dylan, van Opstal, Edward J., Bordenstein, Seth R., 2016
I Contain Multitudes (Ed Yong, Harper Collins) Lean on we: How eco-evolution permeates animal-microbe associations
Trends in Ecology and Evolution, Bordenstein, Seth, 2016
Rethinking heritability of the microbiome
Science, Van Opstal, Edward J., Bordenstein, Seth R., 2015
Bile diversion to the distal small intestine has comparable metabolic benefits to bariatric surgery
Nature Communications, Flynn, Charles Robb, Albaugh, Vance L., Cai, Steven, Cheung-Flynn, Joyce, Williams, Phillip E., Brucker, Robert M., Bordenstein, Seth R., Guo, Yan, Wasserman, David H., Abumrad, Naji N., 2015
Wolbachia co-infection in a hybrid zone: Discovery of horizontal gene transfers fromtwoWolbachia supergroups into an animal genome
PeerJ, Funkhouser-Jones, Lisa J., Sehnert, Stephanie R., Martínez-Rodríguez, Paloma, Toribio-Fernández, Raquel, Pita, Miguel, Bella, José L., Bordenstein, Seth R., 2015
Tandem-repeat protein domains across the tree of life
PeerJ, Jernigan, Kristin K., Bordenstein, Seth R., 2015
Host biology in light of the microbiome: Ten principles of holobionts and hologenomes
PLoS Biology, Bordenstein, Seth R., Theis, Kevin R., 2015
Antibacterial gene transfer across the tree of life
eLife, Metcalf, Jason A., Funkhouser-Jones, Lisa J., Brileya, Kristen, Reysenbach, Anna Louise, Bordenstein, Seth R., 2014
Genomic and cellular complexity from symbiotic simplicity.
Cell, Bordenstein, Seth R., 2014
Response to comment on "the hologenomic basis of speciation: Gut bacteria cause hybrid lethality in the genus Nasonia"
Science, Brucker, Robert, Bordenstein, Seth R., 2014
Early life establishment of site-specific microbial communities in the gut
Gut Microbes, Rromano-Keeler, Joann, Moore, Daniel J., Wang, Chunlin, Brucker, Rrobert M., Fonnesbeck, Christopher, Slaughter, James C., Li, Haijing, Curran, Danielle P., Meng, Shufang, Correa, Hernan, Lovvorn, Harold N., Tang, Yyi Wei, Bordenstein, Seth, George, Aalfred L., Weitkamp, Jörn Hendrik, 2014
Ankyrin domains across the tree of life
PeerJ, Jernigan, Kristin K., Bordenstein, Seth R., 2014
The relative importance of DNA methylation and Dnmt2-mediated epigenetic regulation on Wolbachia densities and cytoplasmic incompatibility
PeerJ, LePage, Daniel P., Jernigan, Kristin K., Bordenstein, Seth R., 2014
Recent genome reduction of Wolbachia in Drosophila recens targets phage WO and narrows candidates for reproductive parasitism
PeerJ, Metcalf, Jason A., Jo, Minhee, Bordenstein, Sarah R., Jaenike, John, Bordenstein, Seth R., 2014
Friends with social benefits: Host-microbe interactions as a driver of brain evolution and development?
Frontiers in cellular and infection microbiology, Stilling, Roman M., Bordenstein, Seth R., Dinan, Timothy G., Cryan, John F., 2014
