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Andrew Read, Ph.D.

  • Evan Pugh Professor of Biology & Entomology,
  • Eberly College of Science Distinguished Senior Scholar
Andrew Read, Ph.D.
W230A Millennium Science Complex
Staff Assistant: Monica Arismendi (mha15@psu.edu +1 814 863-6471)

University Park, PA 16802
Work Phone: 814-867-2396

Education

  1. D.Phil., University of Oxford (1985-1989) [Supervisor: Prof. Paul Harvey FRS]
  2. BSc(Hons) 1st Class in Zoology, University of Otago, New Zealand (1981-1984)

Department Focus Areas:

Disease Ecology and Biology

Research Interests:

Ecology and evolutionary genetics of infectious disease

Research:

My research focuses on the ecology and evolutionary genetics of infectious disease, including:

  • How do public and animal health programs affect pathogen evolution (particularly the evolution of virulence)? 
  • How does host resistance affect pathogen evolution?
  • Will vaccination and chemotherapy prompt the evolution of more virulent pathogens?
  • Can entomopathogenic fungi be used to produce a cheap organic pesticide for sustainable malaria control?
  • Can we make evolution-proof drugs, vaccines and insecticides?
  • How should we use drugs to treat patients when drug treatment leads to resistance?

Current work involves mosquitoes, malaria, Marek's disease, myxomatosis and hospital-acquired bacteria.

More information about my research, from my group website

Awards:

Fellow The Royal Society (elected 2015)
Fellow American Academy of Microbiology (elected 2014)
Fellow of American Association for the Advancement of Science (elected 2012)
Fellow Wissenschaftskolleg zu Berlin (Institute of Advanced Studies) (2006-7) 
Fellow Royal Society of Edinburgh (elected 2003) 

Selected Publications:

Hansen, E., Woods, R.J., & Read, A.F. (2017). How to use a chemotherapeutic agent when resistance to it threatens the patient. PLoS Biology 15: e2001110.

Day, T., & Read A.F. (2016). When does high-dose antimicrobial chemotherapy prevent the emergence of resistance? PLoS Computational Biology 12: e1004689.

Read, A.F., Baigent, S.J., Powers, C., Kgosana, L.B., Blackwell, L., Smith, L.P., Kennedy, D.A., Walkden-Brown, S.W., & Nair, V.K. 2015. Vaccination enhances transmission of highly virulent strains of Marek’s disease virus in chickens. PLoS Biology 13: e1002198.

Huijben, S., Bell, A.S., Sim, D.G., Salathe, R., Tomasello, D., Mideo, N., Day, T. & Read, A.F. 2013. Aggressive chemotherapy and the selection of drug resistant pathogens. PLoS Pathogens 9: e1003578.

Read, A. F., T. Day, and S. Huijben. 2011. The evolution of drug resistance and the curious orthodoxy of aggressive chemotherapy. Proceedings of the National Academy of Sciences USA 108: 10871.

Read, A. F., P. A. Lynch, and M. B. Thomas. 2009. How to build an evolution-proof insecticide for malaria control. PLoS Biology 7: e1000058.

Råberg, L., D. Sim, and A. F. Read. 2007. Disentangling genetic variation for resistance and tolerance to infectious diseases in animals. Science 318: 812.

Blanford, S., B. H. Chan, N. Jenkins, D. Sim, R. J. Turner, A. F. Read, M. B. Thomas. 2005. Fungal pathogen reduces potential for malaria transmission. Science 308: 1638.

More publications from my group website.

Research Interests

Disease Biology and Ecology

Ecology and evolutionary genetics of infectious disease (Center For Infectious Disease Dynamics)

Malaria Research