Andrew Read, Ph.D.

Comparative analysis of multiple consensus genomes of the same strain of Marek's disease virus reveals intrastrain variation
Virus Evolution, Ortigas-Vasquez, Alejandro, Pandey, Utsav, Renner, Daniel W., Bowen, Chris D., Baigent, Susan J., Dunn, John, Cheng, Hans, Yao, Yongxiu, Read, Andrew Fraser, Nair, Venugopal, Kennedy, David A., Szpara, Moriah L., 2024

The evolution of antibiotic resistance in an incurable and ultimately fatal infection: A retrospective case study
Evolution, Medicine and Public Health, Woods, Robert J., Barbosa, Camilo, Koepping, Laura, Raygoza, Juan A., Mwangi, Michael, Read, Andrew F., 2023

Combination antimicrobial therapy to manage resistance
Evolution, Medicine and Public Health, Woods, Robert J., Read, Andrew F., 2023

Divergent Evolutionary Pathways of Myxoma Virus in Australia: Virulence Phenotypes in Susceptible and Partially Resistant Rabbits Indicate Possible Selection for Transmissibility
Journal of Virology, Kerr, Peter J., Cattadori, Isabella M., Sim, Derek, Liu, June, Holmes, Edward C., Read, Andrew F., 2022

Ion Exchange Biomaterials to Capture Daptomycin and Prevent Resistance Evolution in Off-Target Bacterial Populations
ACS applied materials & interfaces, Yeh, Shang Lin, Narasimhalu, Naveen, Vom Steeg, Landon G., Muthami, Joy, Leconey, Sean, He, Zeming, Pitcher, Mica, Cassady, Harrison, Morley, Valerie J., Cho, Sung Hyun, Bator, Carol, Koshani, Roya, Woods, Robert J., Hickner, Michael, Read, Andrew F., Sheikhi, Amir, 2022

Impacts of the COVID-19 pandemic on pharmaceuticals in wastewater treated for beneficial reuse: Two case studies in central Pennsylvania
Journal of Environmental Quality, Hayden, Kathryn, Jones, Matthew, Elkin, Kyle, Shreve, Michael, Clees, William, Clark, Shirley, Mashtare, Michael L., Veith, Tamie, Elliott, Hershel, Watson, J, Silverman, Justin, Richard, Thomas L., Read, Andrew F., Preisendanz, Heather E., 2022

An orally administered drug prevents selection for antibiotic-resistant bacteria in the gut during daptomycin therapy
Evolution, Medicine and Public Health, Morley, Valerie J., Sim, Derek G., Penkevich, Aline, Woods, Robert J., Read, Andrew F., 2022

A longitudinal study of the impact of university student return to campus on the SARS-CoV-2 seroprevalence among the community members
Scientific Reports, Arnold, Callum R.K., Srinivasan, Sreenidhi, Rodriguez, Sophie, Rydzak, Natalie, Herzog, Catherine M., Gontu, Abhinay, Bharti, Nita, Small, Meg, Rogers, Connie J., Schade, Margeaux M., Kuchipudi, Suresh V., Kapur, Vivek, Read, Andrew F., Ferrari, Matthew J., 2022

Pathogen evolution during vaccination campaigns
PLoS Biology, Day, Troy, Kennedy, David, Read, Andrew F., Gandon, Sylvain, 2022

The economics of managing evolution
PLoS Biology, Day, Troy, Kennedy, David A., Read, Andrew F., McAdams, David, 2021

Daptomycin treatment impacts resistance in off-target populations of vancomycin-resistant Enterococcus faecium
PLoS Biology, Kinnear, Clare L., Hansen, Elsa, Morley, Valerie J., Tracy, Kevin C., Forstchen, Meghan, Read, Andrew F., Woods, Robert J., 2020

An adjunctive therapy administered with an antibiotic prevents enrichment of antibiotic-resistant clones of a colonizing opportunistic pathogen
eLife, Morley, Valerie J., Kinnear, Clare, Sim, Derek G., Olson, Samantha N., Olsen, Samantha, Jackson, Lindsey, Hansen, Elsa, Usher, Grace, Showalter, Scott A., Pai, Manjunath, Woods, Robert, Read, Andrew F., 2020

Modifying adaptive therapy to enhance competitive suppression
Cancers, Hansen, Elsa, Read, Andrew F., 2020

Cancer therapy: Attempt cure or manage drug resistance?
Evolutionary Applications, Hansen, Elsa, Read, Andrew F., 2020

Antibiotics can be used to contain drug-resistant bacteria by maintaining sufficiently large sensitive populations
PLoS Biology, Hansen, Elsa, Karslake, Jason, Woods, Robert J., Read, Andrew F., Wood, Kevin B., 2020

Susceptibility of Cutibacterium acnes to topical minocycline foam
Anaerobe, Sutcliffe, Joyce, McLaughlin, Robert, Webster, Guy, Read, Andrew F., Drlica, Karl, Elliott, Russell, Stuart, Iain, 2020

Evolutionary consequences of feedbacks between within-host competition and disease control
Evolution, Medicine and Public Health, Greischar, Megan A., Alexander, Helen K., Bashey, Farrah, Bento, Ana I., Bhattacharya, Amrita, Bushman, Mary, Childs, Lauren M., Daversa, David R., Day, Troy, Faust, Christina L., Gallagher, Molly E., Gandon, Sylvain, Glidden, Caroline K., Halliday, Fletcher W., Hanley, Kathryn A., Kamiya, Tsukushi, Read, Andrew F., Schwabl, Philipp, Sweeny, Amy R., Tate, Ann T., Thompson, Robin N., Wale, Nina, Wearing, Helen J., Yeh, Pamela J., Mideo, Nicole, 2020

Factors associated with antibiotic prescribing for acute bronchitis at a university health center
BMC Infectious Diseases, Morley, Valerie J., Firgens, Emily P.C., Vanderbilt, Rachel R., Zhou, Yanmengqian, Zook, Michelle, Read, Andrew F., MacGeorge, Erina L., 2020

Identifying key questions in the ecology and evolution of cancer
Evolutionary Applications, Dujon, Antoine M., Aktipis, Athena, Alix-Panabières, Catherine, Amend, Sarah R., Boddy, Amy M., Brown, Joel S., Capp, Jean Pascal, DeGregori, James, Ewald, Paul, Gatenby, Robert, Gerlinger, Marco, Giraudeau, Mathieu, Hamede, Rodrigo K., Hansen, Elsa, Kareva, Irina, Maley, Carlo C., Marusyk, Andriy, McGranahan, Nicholas, Metzger, Michael J., Nedelcu, Aurora M., Noble, Robert, Nunney, Leonard, Pienta, Kenneth J., Polyak, Kornelia, Pujol, Pascal, Read, Andrew F., Roche, Benjamin, Sebens, Susanne, Solary, Eric, Staňková, Kateřina, Swain Ewald, Holly, Thomas, Frédéric, Ujvari, Beata, 2020

Effect of drug dose and timing of treatment on the emergence of drug resistance in vivo in a malaria model
Evolution, Medicine and Public Health, Acosta, Mónica M., Bram, Joshua T., Sim, Derek, Read, Andrew F., 2020

Monitor for COVID-19 vaccine resistance evolution during clinical trials
PLoS Biology, Kennedy, David, Read, Andrew F., Kennedy, David A., 2020

Ecology and Medicines, Read, Andrew F., 2020

The contribution of host cell-directed vs. Parasite-directed immunity to the disease and dynamics of malaria infections
Proceedings of the National Academy of Sciences of the United States of America, Wale, Nina, Jones, Matthew J., Sim, Derek G., Read, Andrew F., King, Aaron A., 2019

Bystander Selection for Antimicrobial Resistance: Implications for Patient Health
Trends in Microbiology, Morley, Valerie J., Woods, Robert J., Read, Andrew F., 2019

Impact of an antimicrobial stewardship intervention on within- and between-patient daptomycin resistance evolution in vancomycin-resistant enterococcus faecium
Antimicrobial Agents and Chemotherapy, Kinnear, Clare L., Patel, Twisha S., Young, Carol L., Marshall, Vincent, Newton, Duane W., Read, Andrew F., Woods, Robert J., 2019

Vancomycin-resistant enterococcus acquisition in a tertiary care hospital: Testing the roles of antibiotic use, proton pump inhibitor use, and colonization pressure
Open Forum Infectious Diseases, Chanderraj, Rishi, Millar, Jess A., Patel, Twisha S., Read, Andrew F., Washer, Laraine, Kaye, Keith S., Woods, Robert J., 2019

The plos biology xv collection: 15 years of exceptional science highlighted across 12 months
PLoS Biology, Richardson, Lauren A., Schmid, Sandra L., Bhandoola, Avinash, Harly, Christelle, Hedenström, Anders, Laub, Michael T., Mace, Georgina M., Sengupta, Piali, Stock, Ann M., Read, Andrew F., Malik, Harmit S., Estelle, Mark, Lowell, Sally, Kimmelman, Jonathan, 2019

Punctuated evolution of myxoma virus: Rapid and disjunct evolution of a recent viral lineage in Australia
Journal of Virology, Kerr, Peter J., Eden, John Sebastian, Di Giallonardo, Francesca, Peacock, David, Liu, June, Strive, Tanja, Read, Andrew F., Holmes, Edward C., 2019

Molecular epidemiology of Marek’s disease virus in central Pennsylvania, USA
Virus Evolution, Bell, Andrew S., Kennedy, David A., Jones, Matthew J., Cairns, Christopher L., Pandey, Utsav, Dunn, Patricia A., Szpara, Moriah L., Read, Andrew F., 2019

Modeling Marek's disease virus transmission: A framework for evaluating the impact of farming practices and evolution
Epidemics, Kennedy, David A., Dunn, Patricia A., Read, Andrew F., 2018

Volatile biomarkers of symptomatic and asymptomatic malaria infection in humans
Proceedings of the National Academy of Sciences of the United States of America, De Moraes, Consuelo M., Wanjiku, Caroline, Stanczyk, Nina M., Pulido, Hannier, Sims, James W., Betz, Heike S., Read, Andrew F., Torto, Baldwyn, Mescher, Mark C., 2018

Institution-wide and Within-Patient Evolution of Daptomycin Susceptibility in Vancomycin-Resistant Enterococcus faecium Bloodstream Infections
Infection Control and Hospital Epidemiology, Woods, Robert J., Patel, Twisha S., Nagel, Jerod L., Newton, Duane W., Read, Andrew F., 2018

The impact of within-host ecology on the fitness of a drug-resistant parasite
Evolution, Medicine and Public Health, Huijben, Silvie, Chan, Brian H.K., Nelson, William A., Read, Andrew F., 2018

Why the evolution of vaccine resistance is less of a concern than the evolution of drug resistance
Proceedings of the National Academy of Sciences of the United States of America, Kennedy, David, Read, Andrew F., 2018

Resource limitation prevents the emergence of drug resistance by intensifying within-host competition
Proceedings of the National Academy of Sciences of the United States of America, Wale, Nina, Sim, Derek G., Jones, Matthew J., Salathe, Rahel, Day, Troy, Read, Andrew F., 2017

Reverse engineering field isolates of myxoma virus demonstrates that some gene disruptions or losses of function do not explain virulence changes observed in the field
Journal of Virology, Liu, June, Cattadori, Isabella M., Sim, Derek G., Eden, John Sebastian, Holmes, Edward C., Read, Andrew F., Kerr, Peter J., 2017

Do pathogens gain virulence as hosts become more resistant?
Scientist, Read, Andrew F., Kerr, Peter J., 2017

Next step in the ongoing arms race between myxoma virus and wild rabbits in Australia is a novel disease phenotype
Proceedings of the National Academy of Sciences of the United States of America, Kerr, P, Cattadori, Isabella M., Liu, J, Sim, Derek G., Dodds, Jeff W., Brooks, Jason W., Kennett, Mary J., Holmes, Edward C., Read, Andrew F., 2017

A nutrient mediates intraspecific competition between rodent malaria parasites in vivo
Proceedings of the Royal Society B: Biological Sciences, Wale, Nina, Sim, Derek G., Read, Andrew F., 2017

The selfish germ
PLoS Biology, Read, Andrew F., 2017

Industry-Wide Surveillance of Marek's Disease Virus on Commercial Poultry Farms
Avian Diseases, Kennedy, David A., Cairns, Christopher, Jones, Matthew J., Bell, Andrew S., Salathé, Rahel M., Baigent, Susan J., Nair, Venugopal K., Dunn, Patricia A., Read, Andrew F., 2017

Why does drug resistance readily evolve but vaccine resistance does not?
Proceedings of the Royal Society B: Biological Sciences, Kennedy, David A., Read, Andrew F., 2017

The importance of temperature fluctuations in understanding mosquito population dynamics and malaria risk
Royal Society Open Science, Beck-Johnson, Lindsay M., Nelson, William A., Paaijmans, Krijn P., Read, Andrewf, Thomas, Matthew B., Bjørnstad, Ottar N., 2017

A Murine Model to Study Epilepsy and SUDEP Induced by Malaria Infection
Scientific Reports, Ssentongo, Paddy, Robuccio, Anna E., Thuku, Godfrey, Sim, Derek G., Nabi, Ali, Bahari, Fatemeh, Shanmugasundaram, Balaji, Billard, Myles W., Geronimo, Andrew, Short, Kurt W., Drew, Patrick J., Baccon, Jennifer, Weinstein, Steven L., Gilliam, Frank G., Stoute, José A., Chinchilli, Vernon M., Read, Andrew F., Gluckman, Bruce J., Schiff, Steven J., 2017

Genomic and phenotypic characterization of myxoma virus from Great Britain reveals multiple evolutionary pathways distinct from those in Australia
PLoS Pathogens, Kerr, Peter J., Cattadori, Isabella M., Rogers, Matthew B., Fitch, Adam, Geber, Adam, Liu, June, Sim, Derek G., Boag, Brian, Eden, John Sebastian, Ghedin, Elodie, Read, Andrew F., Holmes, Edward C., 2017

Ecology, Evolution, and the Cancer Patient, Read, Andrew F., 2017

How to Use a Chemotherapeutic Agent When Resistance to It Threatens the Patient
PLoS Biology, Hansen, Elsa, Woods, Robert J., Read, Andrew F., 2017

DNA from dust: Comparative genomics of large DNA viruses in field surveillance samples
mSphere, Pandey, Utsav, Bell, Andrew S., Renner, Daniel W., Kennedy, David A., Shreve, Jacob T., Cairns, Chris L., Jones, Matthew J., Dunn, Patricia A., Read, Andrew F., Szpara, Moriah L., 2016

The threat (or not) of insecticide resistance for malaria control
Proceedings of the National Academy of Sciences of the United States of America, Thomas, Matthew B., Read, Andrew F., 2016

Fitness consequences of altered feeding behavior in immune-challenged mosquitoes
Parasites and Vectors, Ohm, Johanna R., Teeple, Janet, Nelson, William A., Thomas, Matthew B., Read, Andrew F., Cator, Lauren J., 2016

Quantifying Transmission Investment in Malaria Parasites
PLoS Computational Biology, Greischar, Megan A., Mideo, Nicole, Read, Andrew F., Bjørnstad, Ottar N., 2016

Potential drivers of virulence evolution in aquaculture
Evolutionary Applications, Kennedy, David A., Kurath, Gael, Brito, Ilana L., Purcell, Maureen K., Read, Andrew F., Winton, James R., Wargo, Andrew R., 2016

A deep sequencing tool for partitioning clearance rates following antimalarial treatment in polyclonal infections
Evolution, Medicine and Public Health, Mideo, Nicole, Bailey, Jeffrey A., Hathaway, Nicholas J., Ngasala, Billy, Saunders, David L., Lon, Chanthap, Kharabora, Oksana, Jamnik, Andrew, Balasubramanian, Sujata, Bj�rkman, Anders, M�rtensson, Andreas, Meshnick, Steven R., Read, Andrew F., Juliano, Jonathan J., 2016

Does High-Dose Antimicrobial Chemotherapy Prevent the Evolution of Resistance?
PLoS Computational Biology, Day, Troy, Read, Andrew F., 2016

A deep sequencing tool for assessing clearance by antimalarials in polyclonal infections, Mideo, N, Bailey, J., Hathaway, N., Ngasala, B., Saunders, D., Lon, C., Kharabor, O., Jamnik, A., Balasubramanian, S., Björkman, A., Mårtensson, A., Meshnick, S., Read, Andrew, Juliano, J., 2016

DNA from dust: the first field-isolated genomes of MDV-1, from virions in poultry dust and chicken feather follicles, Pandey, U., Bell, A, Renner, D., Kennedy, D, Shreve, J., Cairns, C., Jones, M, Dunn, P, Read, Andrew, Szpara, M, 2016

George C Williams Prize 2015
Evolution, Medicine and Public Health, Read, Andrew F., Bentley, Gillian R., Haig, David, 2016

Population Genetics, Evolutionary Genomics, and Genome-Wide Studies of Malaria: A View across the International Centers of Excellence for Malaria Research
American Journal of Tropical Medicine and Hygiene, Carlton, Jane M., Volkman, Sarah K., Uplekar, Swapna, Hupalo, Daniel N., Pereira Alves, João Marcelo, Cui, Liwang, Donnelly, Martin, Roos, David S., Harb, Omar S., Acosta, Monica, Read, Andrew, Ribolla, Paulo E.M., Singh, Om P., Valecha, Neena, Wassmer, Samuel C., Ferreira, Marcelo, Escalante, Ananias A., 2015

Immune response and insulin signalling alter mosquito feeding behaviour to enhance malaria transmission potential
Scientific Reports, Cator, Lauren J., Pietri, Jose E., Murdock, Courtney C., Ohm, Johanna R., Lewis, Edwin E., Read, Andrew F., Luckhart, Shirley, Thomas, Matthew B., 2015

Existing Infection Facilitates Establishment and Density of Malaria Parasites in Their Mosquito Vector
PLoS Pathogens, Pollitt, Laura C., Bram, Joshua T., Blanford, Simon, Jones, Matthew J., Read, Andrew F., 2015

An observational study of the temporal and spatial patterns of Marek's-disease-associated leukosis condemnation of young chickens in the United States of America
Preventive Veterinary Medicine, Kennedy, David A., Dunn, John R., Dunn, Patricia A., Read, Andrew F., 2015

Relevance of undetectably rare resistant malaria parasites in treatment failure: Experimental evidence from Plasmodium chabaudi
American Journal of Tropical Medicine and Hygiene, Huijben, Silvie, Chan, Brian H.K., Read, Andrew F., 2015

Antibiotic Resistance: A Primer and Call to Action
Health Communication, Smith, Rachel A., M’ikanatha, Nkuchia M., Read, Andrew F., 2015

Understanding genetic variation in in vivo tolerance to artesunate: Implications for treatment efficacy and resistance monitoring
Evolutionary Applications, Pollitt, Laura C., Sim, Derek, Salathé, Rahel, Read, Andrew F., 2015

Clinical management of resistance evolution in a bacterial infection: A case study
Evolution, Medicine and Public Health, Woods, Robert J., Read, Andrew F., 2015

Imperfect vaccination can enhance the transmission of highly virulent pathogens
PLoS Biology, Read, Andrew F., Baigent, Susan J., Powers, Claire, Kgosana, Lydia B., Blackwell, Luke, Smith, Lorraine P., Kennedy, David A., Walkden-Brown, Stephen W., Nair, Venugopal K., 2015

Immune response and insulin signaling alter feeding in the malaria vector Anopheles stephansi., Cator, L., Pietri, J., Murdock, C., Lewis, E., Read, Andrew, Luckhart, S., Thomas, M., Ohm, J., 2015

Is selection relevant in the evolutionary emergence of drug resistance?
Trends in Microbiology, Day, Troy, Huijben, Silvie, Read, Andrew F., 2015

Myxoma virus and the leporipoxviruses: An evolutionary paradigm
Viruses, Kerr, Peter, Liu, June, Cattadori, Isabella, Ghedin, Elodie, Read, Andrew F., Holmes, E, 2015

The path of least resistance: Aggressive or moderate treatment?
Proceedings of the Royal Society B: Biological Sciences, Kouyos, Roger D., Metcalf, C. Jessica E., Birger, Ruthie, Klein, Eili Y., zur Wiesch, Pia Abel, Ankomah, Peter, Arinaminpathy, Nimalan, Bogich, Tiffany L., Bonhoeffer, Sebastian, Brower, Charles, Chi-Johnston, Geoffrey, Cohen, Ted, Day, Troy, Greenhouse, Bryan, Huijben, Silvie, Metlay, Joshua, Mideo, Nicole, Pollitt, Laura C., Read, Andrew F., Smith, David L., Standley, Claire, Wale, Nina, Grenfell, Bryan, 2014

Environmental temperatures significantly change the impact of insecticides measured using WHOPES protocols
Malaria Journal, Glunt, Katey D., Paaijmans, Krijn P., Read, Andrew F., Thomas, Matthew B., 2014

The effect of immunodeficiency on the evolution of virulence: An experimental test with the rodent malaria plasmodium chabaudi
American Naturalist, Barclay, Victoria C., Kennedy, David A., Weaver, Veronika C., Sim, Derek, Lloyd-Smith, James O., Read, Andrew F., 2014

Alterations in mosquito behaviour by malaria parasites: Potential impact on force of infection
Malaria Journal, Cator, Lauren J., Lynch, Penelope A., Thomas, Matthew B., Read, Andrew F., 2014

Immune-Mediated Competition in Rodent Malaria Is Most Likely Caused by Induced Changes in Innate Immune Clearance of Merozoites
PLoS Computational Biology, Santhanam, Jayanthi, Råberg, Lars, Read, Andrew F., Savill, Nicholas Jon, 2014

Malaria-induced changes in host odors enhance mosquito attraction
Proceedings of the National Academy of Sciences of the United States of America, De Moraes, Consuelo M., Stanczyk, Nina M., Betz, Heike S., Pulido, Hannier, Sim, Derek G., Read, Andrew F., Mescher, Mark C., 2014

Rapid Response to Selection, Competitive Release and Increased Transmission Potential of Artesunate-Selected Plasmodium chabaudi Malaria Parasites
PLoS Pathogens, Pollitt, Laura C., Huijben, Silvie, Sim, Derek G., Salathé, Rahel M., Jones, Matthew J., Read, Andrew F., 2014

Synchrony in malaria infections: How intensifying within-host competition can be adaptive
American Naturalist, Greischar, Megan A., Read, Andrew F., Bjørnstad, Ottar N., 2014

Understanding genetic variation in in vivo tolerance to artesunate: implications for treatment efficacy and resistance monitoring., Pollitt, L., Sim, D, Salathe, M, Read, Andrew, 2014

Antibiotic resistance management
Evolution, Medicine and Public Health, Read, Andrew F., Woods, Robert J., 2014