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Jun Miao, Ph.D.

  • Senior Research Associate
Jun Miao, Ph.D.
546 ASI Bldg.
University Park, PA 16802
Email:
Work Phone: 814-863-7660

Education

  1. Ph. D., The Fourth Military Medical University, China, 1999
  2. M.Med.S, The Fourth Military Medical University, China, 1997
  3. M. D., The Fourth Military Medical University, China, 1991

Research Activities & Interests:

Malaria parasite developmental biology, Malaria parasite epigenetics, Vivax malaria population and epidemiology
 

Relevant Publications:

2010

Meng, H., Zhang, R., Yang, H., Miao, J., Fan, Q., Su, X.-z., Cui, L.*, Yang, Z.* 2010. In vitro sensitivity of Plasmodium falciparum clinical isolates from the china-myanmar border area to quinine and association with polymorphism in the Na+/H+ exchanger.  Antimicrob. Agents Chemother.  54, 4306–4313 (*Corresponding author)
 
Miao, J., Li, X. and Cui, L. 2010. Cloning of Plasmodium falciparum by cell sorting.  Exp. Parasitol. 126, 198-202.
 
Cui, L. and Miao J. 2010. Chromatin-mediated gene regulation in malaria parasites. Eukaryot. Cell 9, 1138-1149. (Invited review)

Liwang Cui, Jun Miao. Chromatin-mediated Epigenetic Regulation in the Malaria Parasite Plasmodium falciparum. Eukaryot Cell. 2010 May 7. [Epub ahead of print]

Jun Miao, Xiaolian Li , Liwang Cui. Cloning of Plasmodium falciparum by single-cell sorting. Exp Parasitol. 2010 May 17. [Epub ahead of print]

Jun Miao, Jinfang Li, Fan Qi, Xiaolian Li, Xinyin Li, Liwang Cui. (2010) The Puf Family RNA-Binding Protein PfPuf2 Regulates Sexual Development and Sex Differentiation in the Malaria Parasite Plasmodium falciparum. Journal of Cell Science 123(Pt 7):1039-49.

2009

Qi Fan, Jun Miao, Long Cui, Liwang Cui. (2009) Characterization of Protein Arginine Methyltransferase I from Plasmodium falciparum.  Biochemical Journal. 421(1): 107-18.

Liang Fang*, Xinhai Zhang*, Jun Miao, Fang Zhao, Kun Yang, Ran Zhuang, Hermann Bujard, Angang Yang, Lihua Chen, Boquan Jin. (2009) Expression of CD226 Antagonizes Apoptotic Cell Death in Murine Thymocytes. Journal of Immunology. 182(9): 5453-60.

2008

Jun Miao*, Long Cui*, Tetsuya Furuya, Qi Fan, Xinyi Li, Pradipsinh K. Rathod, Xin-zhuan Su, and Liwang Cui. (2008) Histone Acetyltransferase Inhibitor Anacardic Acid Causes Changes in Global Gene Expression during In Vitro Plasmodium falciparum Development. Eukaryotic Cell. 7(7): 1200-10.

Long Cui, Jun Miao, Jiaxu Wang, Qianjun Li, Liwang Cui. (2008) Plasmodium falciparum: Development of A Transgenic Line for Screening Antimalarials Using Firefly Luciferase as the Reporter. Experimental Parasitology. 120(1): 80-7.

Liwang Cui, Qi Fan, Long Cui, Jun Miao. (2008) Histone Lysine Methyltransferases and Demethylases in Plasmodium falciparum. International Journal of Parasitology. 38(10): 1083-97.

Lijun Liu, Xiayang Xie, Ruizhong Zhang, Ping Xu, Hermann Bujard, Jun Miao. (2008) Reproduction and Fertility in Wild-type and Transgenic Mice after Orthotopic Transplantation of Cryopreserved Ovaries from 10-d-old Mice. Lab Animal (NY). 37(8): 353–7.

2007

Jun Miao*, Long Cui*, Liwang Cui. (2007) Cytotoxic Effect of Curcumin on Malaria Parasite Plasmodium falciparum: Inhibition of Histone Acetylation and Generation of Reactive Oxygen Species. Antimicrobial Agents and Chemotherapy. 51(2): 488-94.

Long Cui, Jun Miao, Tet Fuyoyan, Xinyin Li, Xinzhuan Su, Liwang Cui. (2007) PfGCN5-mediated Histone H3 Acetylation Plays a Key Role in Gene Expression in Plasmodium falciparum. Eukaryotic Cell. 6(7): 1219-27.

2006

Jun Miao, Qi Fan, Long Cui, Junsuo Li, Jianyong Li, Liwang Cui. (2006) The Malaria Parasite Plasmodium Falciparum Histones: Organization, Expression, and Acetylation. Gene. 369: 53-65.
Jun Miao, Xun Li, Zhongxiang Liu, Caifang Xue, Hermann Bujard, Liwang Cui. (2006) Immune Responses in Mice Induced by Prime-boost Schemes of the Plasmodium falciparum Apical Membrane Antigen 1 (PfAMA1)-based DNA, Protein and Recombinant Modified Vaccinia Ankara Vaccines. Vaccine. 24(37-39): 6187-98.

Zhaoqing Yang, Jun Miao, Yaming Huang, Xinyi Li, Chaturong Putaporntip, Somchai Jongwutiwes, Qi Gao, Rachanee Udomsangpetch, Jetsumon Sattabongkot, Liwang Cui . (2006) Genetic Structures of Geographically Distinct Plasmodium vivax Populations Assessed by PCR/RFLP Analysis of the Merozoite Surface Protein 3beta Gene. Acta Tropica. 100(3): 205-12.

*Co-first author